I FOUND SO SO SO MANY OF THEM UNMOTIVATING UNTIL I DISCOVERED SIGNER LAB New Blood: Lab-Grown Stem Cells Bode Well for Transplants, Aging Research https://twitter.com/SignerLab
Mechanistically, syndecan-2 regulates HSC repopulating capacity through control of expression of Cdkn1c (p57) and HSC quiescence. Loss of syndecan-2 expression caused increased HSC cell cycle entry, downregulation of Cdkn1c, and loss of HSC long-term repopulating capacity. Syndecan-2 is a novel marker of HSCs that regulates HSC repopulating capacity via control of HSC quiescence.
neural stem cells DO generate progenitors even in adults - https://www.pennmedicine.org/news/news-releases/2022/july/discovery-of-molecular-signatures-of-immature-neurons-in-the-human-brain