muscle ages, an enzyme called 15-PGDH accumulates and destroys the very signal muscle uses to repair. @Stanford’s Blau lab blocked that enzyme in mice losing weight on semaglutide. The fat still came off. The strength, which the drug alone had cut by nearly 40% after injury, came back.
A drug that switches your repair signal back on does something protein shakes cannot. The muscle problem behind the GLP-1 era finally has a target.