Yes, but the best way is not “buy every exotic gut bug and pray.” Centenarian microbiomes are a pattern, not one magic organism. Reviews commonly mention taxa like Akkermansia, Bifidobacterium, and Christensenellaceae, but the exact mix varies across cohorts, so the smart move is to build an environment that favors them, then add a few targeted organisms on top. (PMC)
My blunt ranking for you, since you already have inulin and Sunfiber/PHGG:
Keep the inulin + PHGG. That is already one of the better “feed the good bugs” bases. Human studies and reviews consistently show inulin-type fructans are bifidogenic, and PHGG also shifts the microbiota in a favorable direction with bifidobacteria-related changes. (PubMed)
Add resistant starch next if you tolerate it. This is probably the cleanest next lever after your current setup. Human trials with resistant potato starch reported increases in Bifidobacterium and Akkermansia after a few weeks. (PubMed)
For Akkermansia specifically, I’d lean toward a pasteurized/postbiotic-style product. The best-known human proof-of-concept used pasteurized A. muciniphila and found improved insulin sensitivity and related metabolic markers. Consumer products now exist in both pasteurized and live formats, but the pasteurized format maps more cleanly onto the headline human trial data. (PubMed)
For Bifidobacterium, buy named strains, not vague “mega blends.” NIH notes probiotics are identified by genus, species, and strain, and health effects depend more on the specific microorganisms than on just total CFU hype. One established example is Bifidobacterium 35624, which is the strain used in current Align products. (Office of Dietary Supplements)
Use polyphenols as the Akkermansia support layer. The literature links dietary polyphenols, especially proanthocyanidin-rich patterns, with higher Akkermansia. Since sugar is annoying and your glucose response to fruit is annoying too, the obvious move is to get that polyphenol piece from lower-sugar sources or extracts, not from force-feeding yourself a berry avalanche. (PubMed)
So the practical stack is:
Base: inulin + PHGG
Next add: resistant starch
Seed layer: pasteurized Akkermansia product
Optional extra seed: a named Bifidobacterium strain product
Adjunct: low-sugar polyphenol source
If you want the shortest possible answer: the best current strategy is “feed first, then seed.” You already have a good start with inulin and Sunfiber. The highest-yield next move is resistant starch, and the most defensible direct supplement target is pasteurized Akkermansia plus a named Bifidobacterium strain. Add one thing at a time, otherwise you will have no idea which expensive powder turned your gut into a protest movement.