3.3.3.2 Diffusion distance of hydroxyl radical
•OH is the most reactive of common ROS. Unsurprisingly, this has the most favorable reduction potential of all common forms of ROS (2.3 V). It is believed to react at close to diffusion-limited rates with numerous substrates (109–1010 M−1s−1;(68,69) e.g., second-order rate constant with GSH = 2.3×1010 M−1s−1). The diffusion distance is around 1–5 nm (i.e. less than the width of a 100 kDa protein
